Biotech / Biomedical: Most Popular Articles
These articles are the most popular over the last month.
Enzymes
An explanation of what enzymes are, their basic structure, and how they function in cellular processes.
An explanation of what enzymes are, their basic structure, and how they function in cellular processes.
Paul Nurse EMBO Interview
Dr. Paul Nurse expresses frank views on the direction of life science research and the challenges facing new drug discovery and development in an interview at the 2012 EMBO Meeting.
Dr. Paul Nurse expresses frank views on the direction of life science research and the challenges facing new drug discovery and development in an interview at the 2012 EMBO Meeting.
Restriction Enzymes Explained
An explanation of a special class of enzymes known as the restriction endonucleases.
An explanation of a special class of enzymes known as the restriction endonucleases.
Everyday Enzyme Products
A list of common products of enzyme biotechnology that are used every day in and around the home, such as paper products, detergents, textiles and foods and beverages. These household items are the result of commercialization of natural and recombinant enzymes produced by genetic protein engineering.
A list of common products of enzyme biotechnology that are used every day in and around the home, such as paper products, detergents, textiles and foods and beverages. These household items are the result of commercialization of natural and recombinant enzymes produced by genetic protein engineering.
What are GMOs?
GMOs are making news nearly every day and issues surrounding their safety are a source of ongoing debate in the food and biotechnology industry. Read about what GMOs are and why they are a source of bioethical controversy.
GMOs are making news nearly every day and issues surrounding their safety are a source of ongoing debate in the food and biotechnology industry. Read about what GMOs are and why they are a source of bioethical controversy.
Tools for Protein Engineering
Essential laboratory procedures for genetic engineering. Molecular genetics techniques commonly used in biotechnology research that enable gene cloning.
Essential laboratory procedures for genetic engineering. Molecular genetics techniques commonly used in biotechnology research that enable gene cloning.
Dairy Industry Enzymes
A description of the types of enzymes used in the dairy industry and their role in the production of cheese, yogurt and other food products.
A description of the types of enzymes used in the dairy industry and their role in the production of cheese, yogurt and other food products.
Make TAE Buffer
Simple instructions on making stock and working solutions of Tris-acetate-EDTA (TAE) buffer for gel electrophoresis.
Simple instructions on making stock and working solutions of Tris-acetate-EDTA (TAE) buffer for gel electrophoresis.
Protein Purification Methods
Methods of protein purification for biotechnology laboratory applications.
Methods of protein purification for biotechnology laboratory applications.
Specific Activity
A definition of specific activity as it applies to proteins and enzyme catalyzed biochemical reactions.
A definition of specific activity as it applies to proteins and enzyme catalyzed biochemical reactions.
Make TBE Buffer
Simple instructions on how to make stock and working solutions of tris-borate-EDTA (TBE) buffer for gel electrophoresis separation of DNA.
Simple instructions on how to make stock and working solutions of tris-borate-EDTA (TBE) buffer for gel electrophoresis separation of DNA.
Make a Phosphate Buffer
Follow these instructions on how to make phosphate buffers for biological applications at near neutral pH, or adapt them for making any other buffer using a weak acid / conjugate base pair.
Follow these instructions on how to make phosphate buffers for biological applications at near neutral pH, or adapt them for making any other buffer using a weak acid / conjugate base pair.
siRNA and miRNA
Is there a difference between small interfering RNA (siRNA) and micro RNA (miRNA)?
Is there a difference between small interfering RNA (siRNA) and micro RNA (miRNA)?
Adverse Events Reports
Find out what a SUSAR is and what the list of the qualifiers are for filing a SUSAR during a clinical drug trial.
Find out what a SUSAR is and what the list of the qualifiers are for filing a SUSAR during a clinical drug trial.
Stem Cell Pros and Cons
A discussion of the pros and cons in the ethical debate over embryonic stem cell research and biomedical research using other types of stem cells.
A discussion of the pros and cons in the ethical debate over embryonic stem cell research and biomedical research using other types of stem cells.
Sodium Citrate Buffer
Six simple steps to make sodium citrate buffer for RNA isolation or antigen detection.
Six simple steps to make sodium citrate buffer for RNA isolation or antigen detection.
Polymerase Chain Reaction
Learn the basic theory behind the polymerase chain reaction, or PCR technique for making multiple copies of a gene from a sample of DNA.
Learn the basic theory behind the polymerase chain reaction, or PCR technique for making multiple copies of a gene from a sample of DNA.
DNA Sequencing Methods
Different DNA sequencing methods described.
Different DNA sequencing methods described.
Make a Tris Buffer
Tris is a chemical with basic properties, having a pKa of 8.1. It can be used to buffer solutions from drastic pH changes, keeping them in the pH range of 7.0 to 9.0. Make any Tris-HCl buffer in this pH range, at any molarity using these simple steps.
Tris is a chemical with basic properties, having a pKa of 8.1. It can be used to buffer solutions from drastic pH changes, keeping them in the pH range of 7.0 to 9.0. Make any Tris-HCl buffer in this pH range, at any molarity using these simple steps.
GM Food Controversy
Although genetically modified (GM) food has been on supermarket shelves for almost 15 years, there is still extensive controversy about whether it is safe. Anti-GM group continue to sound the alarm regarding its potential risks dangerous. Why is there such controversy about GM food and crops and is there still a reason to be concerned about its safety? Take a look at this article to get an overview of what is driving this discussion.
Although genetically modified (GM) food has been on supermarket shelves for almost 15 years, there is still extensive controversy about whether it is safe. Anti-GM group continue to sound the alarm regarding its potential risks dangerous. Why is there such controversy about GM food and crops and is there still a reason to be concerned about its safety? Take a look at this article to get an overview of what is driving this discussion.
GMO Food and World Hunger
Advocates for genetic engineering of crops used for food point to benefits such as providing better and more nutritious, potentially solving world hunger by increasing crop yields, fortifying foods to ensure the poor are getting proper nutrition. However, genetically modified (GM) foods have been available since the mid-nineties. Has their adoption really impacted world hunger? What's really driving the rapid adoption of GM food and is it part of the answer to feed a hunger world?
Advocates for genetic engineering of crops used for food point to benefits such as providing better and more nutritious, potentially solving world hunger by increasing crop yields, fortifying foods to ensure the poor are getting proper nutrition. However, genetically modified (GM) foods have been available since the mid-nineties. Has their adoption really impacted world hunger? What's really driving the rapid adoption of GM food and is it part of the answer to feed a hunger world?
Boston vs. San Francisco Biotech
Looks at the details of the two regions with the highest density of biotech companies and most people working in biotech—the San Francisco Bay and Boston, Massachusetts regions. How do these two regions compare in terms of the types of biotech companies, size of biotech communities, and amount of biotech investment?
Looks at the details of the two regions with the highest density of biotech companies and most people working in biotech—the San Francisco Bay and Boston, Massachusetts regions. How do these two regions compare in terms of the types of biotech companies, size of biotech communities, and amount of biotech investment?
Participate in a Drug Trial
Links to websites listing current and upcoming drug trials and how to become a participating subject. In addition, some sites contain new drug approval news, information on drug interactions, and clinical research job listings.
Links to websites listing current and upcoming drug trials and how to become a participating subject. In addition, some sites contain new drug approval news, information on drug interactions, and clinical research job listings.
Proteins
A brief explanation of what proteins are, their composition and the many roles they play in cellular processes.
A brief explanation of what proteins are, their composition and the many roles they play in cellular processes.
Separate DNA With Agarose Gels
Follow these simple steps for running an agarose gel to separate and visualize different size DNA strands.
Follow these simple steps for running an agarose gel to separate and visualize different size DNA strands.
Prenatal Tests with Maternal Blood
A simple blood test of a pregnant woman can now identify fetal genetic abnormalities that can produce conditions such as Down's Syndrome. How was this approach developed and who are the companies involved in developing the technology?
A simple blood test of a pregnant woman can now identify fetal genetic abnormalities that can produce conditions such as Down's Syndrome. How was this approach developed and who are the companies involved in developing the technology?
Transcription Factors
Transcription factors are important molecules, usually proteins, involved in controlling gene expression by RNA polymerase. In eukaryotic cells they bind to promoter regions on the DNA.
Transcription factors are important molecules, usually proteins, involved in controlling gene expression by RNA polymerase. In eukaryotic cells they bind to promoter regions on the DNA.
Reasons to use E. coli
Five reasons the microorganism E. coli is so widely used in protein engineering and genetic research.
Five reasons the microorganism E. coli is so widely used in protein engineering and genetic research.
RFLP
A description of the molecular technique known as RFLP and brief explanation of the theory behind the methodology.
A description of the molecular technique known as RFLP and brief explanation of the theory behind the methodology.
Reasons to Get ISO QMS
Ten reasons why your company should be certified for ISO 9001:2000 Quality Management Standards (QMS).
Ten reasons why your company should be certified for ISO 9001:2000 Quality Management Standards (QMS).
Agricultural Biotech
A list of agricultural applications for biotechnology research.
A list of agricultural applications for biotechnology research.
PCR
A definition of the molecular technique known as PCR and its usefulness in various biotechnology applications, forensic science and environmental research.
A definition of the molecular technique known as PCR and its usefulness in various biotechnology applications, forensic science and environmental research.
Polymorphism
The genetic term polymorphism refers to the discovery that there may be several variations in gene sequence for a specific protein.
The genetic term polymorphism refers to the discovery that there may be several variations in gene sequence for a specific protein.
Microinjection
Use of DNA microinjection techniques for gene transfer and creation of transgenic animals.
Use of DNA microinjection techniques for gene transfer and creation of transgenic animals.
DNA Stains
A list of the different dyes or stains for visualizing DNA.
A list of the different dyes or stains for visualizing DNA.
PBS Buffer
PBS is a commonly used buffer for immunohistochemical (IHC) staining, used as a wash solution and for diluting antibodies.
PBS is a commonly used buffer for immunohistochemical (IHC) staining, used as a wash solution and for diluting antibodies.
Nanoparticles
Nanoparticles used in nanomedical research and other biotechnological applications.
Nanoparticles used in nanomedical research and other biotechnological applications.
Hydrolysis
A definition for enzyme hydrolysis, to explain what kind of biochemical reaction hydrolases catalyze and how that is useful to biotechnology applications.
A definition for enzyme hydrolysis, to explain what kind of biochemical reaction hydrolases catalyze and how that is useful to biotechnology applications.
Determining Titer
A simple explanation of how titer is determined, during bioproduct production in the biomedical industry, for antibodies, other proteins and other biological substances.
A simple explanation of how titer is determined, during bioproduct production in the biomedical industry, for antibodies, other proteins and other biological substances.
Fermentation
A broad definition of fermentation in both general and more scientific terms.
A broad definition of fermentation in both general and more scientific terms.
DNA Fingerprinting
Explanation of the term DNA fingerprinting and a brief description of the methodology.
Explanation of the term DNA fingerprinting and a brief description of the methodology.
Nanomedicine
How nanotechnology is being applied to nanomedicine and the treatment of diseases such as cancer.
How nanotechnology is being applied to nanomedicine and the treatment of diseases such as cancer.
Science and Law
The high demand for legal professionals with science and technology backgrounds is explained and career expectations for individuals studying science and law are discussed.
The high demand for legal professionals with science and technology backgrounds is explained and career expectations for individuals studying science and law are discussed.
siRNA
What is siRNA, or small interfering RNA and how is it used as a molecular genetics research tool in the process called RNA interference?
What is siRNA, or small interfering RNA and how is it used as a molecular genetics research tool in the process called RNA interference?
Reverse Transcriptase PCR
RT-PCR can mean one of two things in biotechnology. Here's one of the definitions.
RT-PCR can mean one of two things in biotechnology. Here's one of the definitions.
Superior PCR
Adjustments to any of the components of a PCR reaction can alter the quality of the outcome, either improving or diminishing the product yield and quality, or reaction specificity and sensitivity. Parameters that influence the end result can be either physical (i.e. temperature, cycle times) or chemical (i.e. nucleotide or template concentration, type of polymerase enzyme used). The following are several key factors that influence the success of PCR.
Adjustments to any of the components of a PCR reaction can alter the quality of the outcome, either improving or diminishing the product yield and quality, or reaction specificity and sensitivity. Parameters that influence the end result can be either physical (i.e. temperature, cycle times) or chemical (i.e. nucleotide or template concentration, type of polymerase enzyme used). The following are several key factors that influence the success of PCR.
Parkinson's
Parkinsonâs is a neurodegenerative disease that appears when certain nerve cells of the brain, in a region
Parkinsonâs is a neurodegenerative disease that appears when certain nerve cells of the brain, in a region
Bioremediation
Bioremediation is explained as a branch of environmental biotechnology in which contaminated soil, air and water are treated.
Bioremediation is explained as a branch of environmental biotechnology in which contaminated soil, air and water are treated.
Retroviruses
Retroviruses are a special type of RNA virus, that replicate their genome by reverse transcription of their RNA to form DNA which is then incorporated into the genome and transcribed by the host cells which the virus inhabits.
Retroviruses are a special type of RNA virus, that replicate their genome by reverse transcription of their RNA to form DNA which is then incorporated into the genome and transcribed by the host cells which the virus inhabits.
Discovery of Genes
Experiments with chromosomal material that were primarily responsible for the establishment of DNA as the component that encodes for the structures of proteins.
Experiments with chromosomal material that were primarily responsible for the establishment of DNA as the component that encodes for the structures of proteins.
Early Biotechnology
There are many important discoveries that have played big roles in the evolution of the biotechnology
There are many important discoveries that have played big roles in the evolution of the biotechnology
Vectors
Vectors are tools for gene transfer during cloning.
Vectors are tools for gene transfer during cloning.
Business Models
Platform, Product and Vertical strategies make up three major biotechnology business models.
Platform, Product and Vertical strategies make up three major biotechnology business models.
Epigenetic Inheritance
Can a parent's life experience affect the genetic traits they pass onto their children? While gene sequences don't change with life experience, epigenetic mark-ups that specific gene expression patterns do, and these changes are sometime heritable.
Can a parent's life experience affect the genetic traits they pass onto their children? While gene sequences don't change with life experience, epigenetic mark-ups that specific gene expression patterns do, and these changes are sometime heritable.
Transformation
Transformation refers to changes in the genetic makeup of a normal cell either through insertion of foreign DNA into a chromosome, or by an alteration that causes tumor cell-like behavior.
Transformation refers to changes in the genetic makeup of a normal cell either through insertion of foreign DNA into a chromosome, or by an alteration that causes tumor cell-like behavior.
How GMOs Are Made
If you want to understand the basic procedure for genetically engineering plants and animals, take a look at this article.
If you want to understand the basic procedure for genetically engineering plants and animals, take a look at this article.
Bioindicators
An introduction to bioindicators and how they are used in the biotechnology industry to detect physiological responses to cellular stressors.
An introduction to bioindicators and how they are used in the biotechnology industry to detect physiological responses to cellular stressors.
Genome Sequencing Business
For several hundred to several thousand dollars, you can go online and order a service kit to have your DNA analyzed. How does this work? What do these companies provide and what do you have to do? This article explains direct to consumer genetic analysis.
For several hundred to several thousand dollars, you can go online and order a service kit to have your DNA analyzed. How does this work? What do these companies provide and what do you have to do? This article explains direct to consumer genetic analysis.
Biotech and Food Production
food biotechnology, antibiotic plastics, packaging, gmos, transgenic plants, pathogen resistance, potable water, cryptosporidium, monoclonal antibodies, lycopene, tomatoes, siRNA, hydrogenated oil, vegetable oils, stearic acid, saturated fatty acids, smart polymers, biofilms, food, water, pathogens, antibodies, oils
food biotechnology, antibiotic plastics, packaging, gmos, transgenic plants, pathogen resistance, potable water, cryptosporidium, monoclonal antibodies, lycopene, tomatoes, siRNA, hydrogenated oil, vegetable oils, stearic acid, saturated fatty acids, smart polymers, biofilms, food, water, pathogens, antibodies, oils
GM Food: How Did We Get Here?
Starting with the launch of the Flavr Savr Tomato, the first genetically modified organism (GMO) approved for sale as food in the mid-1990s, food containing GMOs has become a significant part of the stock in US, Canadian, and Asian grocery stores. About 70% of US processed food sold contains genetically modified (GM) crops. A revolution in food science and production has been taking place over the past two decades. How did we get here?
Starting with the launch of the Flavr Savr Tomato, the first genetically modified organism (GMO) approved for sale as food in the mid-1990s, food containing GMOs has become a significant part of the stock in US, Canadian, and Asian grocery stores. About 70% of US processed food sold contains genetically modified (GM) crops. A revolution in food science and production has been taking place over the past two decades. How did we get here?
Transcription
Transcription is the first step in gene expression, resulting in the formation of RNA and, ultimately protein synthesis.
Transcription is the first step in gene expression, resulting in the formation of RNA and, ultimately protein synthesis.
Tools for RFLP
Molecular techniques that make it possible to perform RFLP analysis.
Molecular techniques that make it possible to perform RFLP analysis.
Financing a Startup
An outline suggesting five funding sources for financing a new startup Biotech company.
An outline suggesting five funding sources for financing a new startup Biotech company.
Biotech Overview
This article provides a summary or overview of biotechnology or biotech with a description of the start of biotechnology, development of commercial biotechnology, and an overview of the biotech industry. It includes brief summaries of the methods that comprise biotechnology and genetic engineering, biotechnology companies, the medical biotech and agricultural biotechnology industry segments, what a biotech start-up is, GMOs, transgenic organisms, and the connection between biotechnology and drug development.
This article provides a summary or overview of biotechnology or biotech with a description of the start of biotechnology, development of commercial biotechnology, and an overview of the biotech industry. It includes brief summaries of the methods that comprise biotechnology and genetic engineering, biotechnology companies, the medical biotech and agricultural biotechnology industry segments, what a biotech start-up is, GMOs, transgenic organisms, and the connection between biotechnology and drug development.
Xenotransplantation
An explanation for xenotransplantation and the bioethical issues surrounding the use of animal organs and tissues for human transplants.
An explanation for xenotransplantation and the bioethical issues surrounding the use of animal organs and tissues for human transplants.
Choosing Biotech Stocks
Investing in biotechnology can be a risky business. The following list outlines some suggested criteria to consider when choosing which biotech stocks to buy.
Investing in biotechnology can be a risky business. The following list outlines some suggested criteria to consider when choosing which biotech stocks to buy.
Invest in Biotech
Pointers on how to invest in biotech with things to consider before investing in biotech companies or buying biotechnology stocks.
Pointers on how to invest in biotech with things to consider before investing in biotech companies or buying biotechnology stocks.
Next Generation Sequencing
The DNA Sequencing Market According to Life Science Market research firm Decibio , the DNA sequencing
The DNA Sequencing Market According to Life Science Market research firm Decibio , the DNA sequencing
ISO Certification
Explanation of the ISO standards and QMS certification
Explanation of the ISO standards and QMS certification
Orphan Drugs
Orphan Drug Status is given to certain drugs undergoing development in the pharmaceutical industry. Find out what Orphan Drug Status is and what incentives are available to biotech companies obtaining this designation from the US FDA.
Orphan Drug Status is given to certain drugs undergoing development in the pharmaceutical industry. Find out what Orphan Drug Status is and what incentives are available to biotech companies obtaining this designation from the US FDA.
Xenotransplants
A discussion of the ethical and practical issues surrounding the use of animal organs for human transplants (xenotransplantation).
A discussion of the ethical and practical issues surrounding the use of animal organs for human transplants (xenotransplantation).
Thermophilic
A definition of the term thermophilic, as it applies to biotechnology research and industrial applications using microorganisms and their enzymes from extreme environments.
A definition of the term thermophilic, as it applies to biotechnology research and industrial applications using microorganisms and their enzymes from extreme environments.
Polymers
An explanation for what polymers are and their monomer composition. A definition including descriptions of different types of natural (carbohydrate, protein) and synthetic (plastics) polymers.
An explanation for what polymers are and their monomer composition. A definition including descriptions of different types of natural (carbohydrate, protein) and synthetic (plastics) polymers.
Epigenetics
A definition of the term epigenetics, and how epigenetic marks in eukaryotes control transcription. Also discussed are the relationships between studies of how gene expression is regulated, stem cell research, and cloning.
A definition of the term epigenetics, and how epigenetic marks in eukaryotes control transcription. Also discussed are the relationships between studies of how gene expression is regulated, stem cell research, and cloning.
Choosing Electrophoresis Buffer
There are different types of buffers you can use for agarose gel electrophoresis. Here's how to decide which one to use.
There are different types of buffers you can use for agarose gel electrophoresis. Here's how to decide which one to use.
Fullerenes
Carbon nanotubes and buckyballs belong to a class of carbon-based nanoparticles known as the fullerenes.
Carbon nanotubes and buckyballs belong to a class of carbon-based nanoparticles known as the fullerenes.
Roles of Venture Investors
A list of the roles that biotech venture investors play in the development of early- and mid-stage startups. The benefits, and some of the shortfalls, to obtaining venture capital funding for R&D and to promote the growth of a company, are outlined.
A list of the roles that biotech venture investors play in the development of early- and mid-stage startups. The benefits, and some of the shortfalls, to obtaining venture capital funding for R&D and to promote the growth of a company, are outlined.
Titer
A definition for titer as it applies to the biomedical industry and production of antibodies, proteins, antibiotics and other bioproducts.
A definition for titer as it applies to the biomedical industry and production of antibodies, proteins, antibiotics and other bioproducts.
Get ISO 9001:2000 QMS
Follow these steps to becoming ISO certified for 9001:2000 Quality Management Standards (QMS).
Follow these steps to becoming ISO certified for 9001:2000 Quality Management Standards (QMS).
Pipelines
An explanation for what pipelines are as they apply to new drug development in the biotechnology industry and how they are used to describe the research and development progress of biotech companies.
An explanation for what pipelines are as they apply to new drug development in the biotechnology industry and how they are used to describe the research and development progress of biotech companies.
2012 Global Biotech Report
The Ernst and Young annual report on the global biotech industry indicates the biotech industry has recovered a lot from the dismal 2009 crisis. Revenues, R&D investment, and hiring are all up. However, beneath the surface the numbers suggest some long term changes in biotech/pharma industry.
The Ernst and Young annual report on the global biotech industry indicates the biotech industry has recovered a lot from the dismal 2009 crisis. Revenues, R&D investment, and hiring are all up. However, beneath the surface the numbers suggest some long term changes in biotech/pharma industry.
IPSCs
A quick discussion on what IPSCs are and how they are used in stem cell research, regenerative medicine and tissue engineering.
A quick discussion on what IPSCs are and how they are used in stem cell research, regenerative medicine and tissue engineering.
Germ Line Gene Therapy
As the first gene therapy approaches are nearing FDA approval, it is important to make the distinction between somatic cell and germ line genetic manipulation. Although therapies on sperm and egg cells have tremendous potential, they would require a much more thorough understanding than our current science possesses. Will germ line gene therapy ever be an option?
As the first gene therapy approaches are nearing FDA approval, it is important to make the distinction between somatic cell and germ line genetic manipulation. Although therapies on sperm and egg cells have tremendous potential, they would require a much more thorough understanding than our current science possesses. Will germ line gene therapy ever be an option?
Impact DNA Sequencing on Health Care
As DNA sequencing costs are coming down to the point where this technology can transition from basic research to a routine medical use, there is a lot of discussion how this new in depth information genetic will really affect health care. A couple new studies demonstrate how this technology could be practically used to improve health care of individuals in the next few years.
As DNA sequencing costs are coming down to the point where this technology can transition from basic research to a routine medical use, there is a lot of discussion how this new in depth information genetic will really affect health care. A couple new studies demonstrate how this technology could be practically used to improve health care of individuals in the next few years.
Bioethics
The term bioethics defined.
The term bioethics defined.
The Research Lab to Clinic Gap
Advances in molecular analysis are poised to revolutionize medicine, but the changes are causing some growing pains. Research is advancing faster than ever with new data coming in all the time, and medicine is struggling to keep up. Will patients be able to reap the benefit of new discoveries in a timely manner? Only with some changes to the system.
Advances in molecular analysis are poised to revolutionize medicine, but the changes are causing some growing pains. Research is advancing faster than ever with new data coming in all the time, and medicine is struggling to keep up. Will patients be able to reap the benefit of new discoveries in a timely manner? Only with some changes to the system.
Sustainability
Sustainability is defined in terms of corporate activities and sustainabile business approaches that take into account the environmental, social and economic impacts of decisions and processes.
Sustainability is defined in terms of corporate activities and sustainabile business approaches that take into account the environmental, social and economic impacts of decisions and processes.
Active Ingredients
Active ingredients refers to the chemical makeup of drugs.
Active ingredients refers to the chemical makeup of drugs.
Biotechnology Clusters in NA
A list of the top biotechnology hubs in North America. Each cluster is an active site of R&D, job and investment opportunities in the life sciences or agricultural biotech.
A list of the top biotechnology hubs in North America. Each cluster is an active site of R&D, job and investment opportunities in the life sciences or agricultural biotech.
Knockouts
Gene knockouts are useful tools for studying the causes of genetic diseases, but what exactly are they?
Gene knockouts are useful tools for studying the causes of genetic diseases, but what exactly are they?
What is Zoning?
An explanation of what zoning is, and how it affects commercial land use.
An explanation of what zoning is, and how it affects commercial land use.
Plasmids
The role of plasmids as vectors for gene transfer.
The role of plasmids as vectors for gene transfer.
Drought Tolerant Corn
Three strains of drought resistant corn are current making their way to farmer’s fields. Two of the strains, from Syngenta and Pioneer, were developed using advanced genetic breeding approaches, whereas Monsanto’s corn was developed using genetic engineering. While both approaches were somewhat successful, it is clear these are the first generation of these plant hybrids. It is likely that further improvements could be made using each approach or a combination of the two.
Three strains of drought resistant corn are current making their way to farmer’s fields. Two of the strains, from Syngenta and Pioneer, were developed using advanced genetic breeding approaches, whereas Monsanto’s corn was developed using genetic engineering. While both approaches were somewhat successful, it is clear these are the first generation of these plant hybrids. It is likely that further improvements could be made using each approach or a combination of the two.
Virtual Businesses
Virtual companies are formed using a business model that takes advantage of the availability of suitable contract organizations for outsourcing all aspects of the biotechnology business.
Virtual companies are formed using a business model that takes advantage of the availability of suitable contract organizations for outsourcing all aspects of the biotechnology business.
Phytoremediation
Descriptions for six different types of phytoremediation.
Descriptions for six different types of phytoremediation.
Translation
The second step in the protein synthesis process, wherein the genetic code of the transcribed mRNA sequence is translated by ribosomes into a polypeptide sequence.
The second step in the protein synthesis process, wherein the genetic code of the transcribed mRNA sequence is translated by ribosomes into a polypeptide sequence.
Smart Polymers
A description of the possible and current uses for smart polymers in the biotechnology industry. Types of stimulus responsive polymers and nanoparticles are explained and their potential for use in biomedicine is discussed.
A description of the possible and current uses for smart polymers in the biotechnology industry. Types of stimulus responsive polymers and nanoparticles are explained and their potential for use in biomedicine is discussed.
Write a Business Plan
Every biotech startup should begin with a thorough business plan to guide the achievement of milestones and obtaining research funding by satisfying potential venture and angel investors, granting agencies and loan institutions. Check this planning outline for a list of items to include in your business plan.
Every biotech startup should begin with a thorough business plan to guide the achievement of milestones and obtaining research funding by satisfying potential venture and angel investors, granting agencies and loan institutions. Check this planning outline for a list of items to include in your business plan.
Freeze Dry a Culture
Quick step by step instructions for preservation of bacterial, fungal or yeast cell cultures, by freeze drying (lyophilization).
Quick step by step instructions for preservation of bacterial, fungal or yeast cell cultures, by freeze drying (lyophilization).
Lyophilization
A definition of lyophilization as it applies to the preservation and storage of microbial cell cultures.
A definition of lyophilization as it applies to the preservation and storage of microbial cell cultures.
Hepatitis C
An explanation of the viral infection Hepatitis C including causes and symptoms of the disease.
An explanation of the viral infection Hepatitis C including causes and symptoms of the disease.
What is Biotechnology?
Definition of biotechnology and a description of the various aspects of the biotech industry.
Definition of biotechnology and a description of the various aspects of the biotech industry.
Blastocyst
Blastocyst definition and a description of how embryos at this stage of development are used in stem cell research.
Blastocyst definition and a description of how embryos at this stage of development are used in stem cell research.
EY 2013 Biotech Report
The EY 2013 report on the biotech industry was released at the BIO 2013 Conference. The study shows that, while the sector saw record profits this past year, there are a couple worrying trends. (Posted: April 25, 2013)
The EY 2013 report on the biotech industry was released at the BIO 2013 Conference. The study shows that, while the sector saw record profits this past year, there are a couple worrying trends. (Posted: April 25, 2013)
Enzyme Optimization
Four approaches to optimizing an enzyme process for commercial production, ranging from natural selection to fine-tuned molecular-level genetic manipulations.
Four approaches to optimizing an enzyme process for commercial production, ranging from natural selection to fine-tuned molecular-level genetic manipulations.
SWOT
A SWOT analysis is a business tool for strategic planning.
A SWOT analysis is a business tool for strategic planning.
What are Vero Cells?
An explanation of the vero cell line and the use of vero cells in generating vaccines.
An explanation of the vero cell line and the use of vero cells in generating vaccines.
The Skills for a Startup
Advice to those interested in a career in biotechnology, with a biotech startup, or looking to start their own company. Biotech startups require innovative, versatile people able to fulfill a variety of responsibilities and do a lot of different jobs, like the ones listed here.
Advice to those interested in a career in biotechnology, with a biotech startup, or looking to start their own company. Biotech startups require innovative, versatile people able to fulfill a variety of responsibilities and do a lot of different jobs, like the ones listed here.
Advantages to Hydrogels
Once used for simple encapsulation of cells or drugs, in homogeneous materials, todays hydrogels are more complex smart polymers with different types of ligands and cross-links allowing for highly regulated structures and different bioresponsive functionalities. What makes hydrogels such a great choice for development of therapeutic devices?
Once used for simple encapsulation of cells or drugs, in homogeneous materials, todays hydrogels are more complex smart polymers with different types of ligands and cross-links allowing for highly regulated structures and different bioresponsive functionalities. What makes hydrogels such a great choice for development of therapeutic devices?
Human Genome
In 1990, a project was initiated to determine the entire sequence of DNA making up the human genome. The human genome project involved participants from laboratories worldwide and resulted in significant advances in DNA screening and sequencing technologies, in addition to the discovery of thousands of new genes.
In 1990, a project was initiated to determine the entire sequence of DNA making up the human genome. The human genome project involved participants from laboratories worldwide and resulted in significant advances in DNA screening and sequencing technologies, in addition to the discovery of thousands of new genes.
Reasons to do a Ph.D.
For those considering doctoral studies, here are five reasons to go all the way in graduate school and complete a Ph.D.
For those considering doctoral studies, here are five reasons to go all the way in graduate school and complete a Ph.D.
Liposomes
Liposomes are phospholipid bilayers that have formed a closed vesicle. Polymeric micelles are a type of nanoparticle that can be used for drug delivery.
Liposomes are phospholipid bilayers that have formed a closed vesicle. Polymeric micelles are a type of nanoparticle that can be used for drug delivery.
Used Lab Equipment
A list of resources and suggestions for finding used lab equipment.
A list of resources and suggestions for finding used lab equipment.
Impact Gene Patent Decision
While much has been made about how the decision in the Myriad Gene Patenting lawsuit will affect the biotech industry and biomedical research, how much impact will it actually have? (Published: April 30, 2013)
While much has been made about how the decision in the Myriad Gene Patenting lawsuit will affect the biotech industry and biomedical research, how much impact will it actually have? (Published: April 30, 2013)
Bioplastics
Like biomass plastics, bioplastics are made by fermentation of sugars obtained from plants, but bioplastics are biodegradable because their polymers are different from petroleum-derived plastics.
Like biomass plastics, bioplastics are made by fermentation of sugars obtained from plants, but bioplastics are biodegradable because their polymers are different from petroleum-derived plastics.
Cancer
A brief description of cancer, progression of the disease, and possible causes.
A brief description of cancer, progression of the disease, and possible causes.
Common Biotech Terms
You read about advances in biotechnology every day in the newspaper, and hear about it on TV, but sometimes
You read about advances in biotechnology every day in the newspaper, and hear about it on TV, but sometimes
Biomedical Research Reliability
Recent studies suggest much of published biomedical research is not reproducible, in fact, there seem to be problems with most studies. What’s the problem with science and how reliable are published results?
Recent studies suggest much of published biomedical research is not reproducible, in fact, there seem to be problems with most studies. What’s the problem with science and how reliable are published results?
Novozymes
A case study on the Danish bioproducts company, Novozymes, a global leader in enzyme technology, and producer of recombinant enzymes for industrial uses such as detergents, animal feed and biofuel production. The former leader in insulin production is renowned for its focus on environmental and social sustainability.
A case study on the Danish bioproducts company, Novozymes, a global leader in enzyme technology, and producer of recombinant enzymes for industrial uses such as detergents, animal feed and biofuel production. The former leader in insulin production is renowned for its focus on environmental and social sustainability.
Underlying Causes of Cancer
With recent technology advances, researchers are able to gather much more data about the particular changes in cells that produce cancer. Making sense of the massive amount of data, though, is the difficulty. Read how molecular science is changing how cancer is characterized.
With recent technology advances, researchers are able to gather much more data about the particular changes in cells that produce cancer. Making sense of the massive amount of data, though, is the difficulty. Read how molecular science is changing how cancer is characterized.
In vivo electroporation
How does in vivo electroporation work for DNA vaccine delivery?
How does in vivo electroporation work for DNA vaccine delivery?
Designer Babies
Developments in stem cell research and in vitro techniques for reproduction have led us to the theory that sometime in the near future, wanna-be parents will be able to create designer babies with the specific traits they desire.
Developments in stem cell research and in vitro techniques for reproduction have led us to the theory that sometime in the near future, wanna-be parents will be able to create designer babies with the specific traits they desire.
DTC Genetic Testing Profiles
Find out about the growing niche of companies that offer personal genetic analysis which provides information about disease risks, health conditions, ancestry, and other individual traits. This developing direct-to-consumer (DTC) DNA analysis business breaks old models of how health tests are provided and offers any individual direct access to sophisticated DNA results.
Find out about the growing niche of companies that offer personal genetic analysis which provides information about disease risks, health conditions, ancestry, and other individual traits. This developing direct-to-consumer (DTC) DNA analysis business breaks old models of how health tests are provided and offers any individual direct access to sophisticated DNA results.
Affymetrix Profile
The company that introduced microarray technology for genetic analysis is facing hard times as much of the market is supplanted by next generation sequencing. Does Affymetrix have a plan?
The company that introduced microarray technology for genetic analysis is facing hard times as much of the market is supplanted by next generation sequencing. Does Affymetrix have a plan?
Ligands
A descriptive definition of ligands and the role they play in biotechnology, particularly in relation to enzyme functions and the catalysis of biochemical reactions.
A descriptive definition of ligands and the role they play in biotechnology, particularly in relation to enzyme functions and the catalysis of biochemical reactions.
What is DNA?
What is DNA and what does it do?
What is DNA and what does it do?
Fireflies and Biotechnology
Fireflies are nocturnal flying beetles that generate light in their abdomen, via a chemical reaction. Find out how firefly luminescence has become a widely used tool in biotechnology.
Fireflies are nocturnal flying beetles that generate light in their abdomen, via a chemical reaction. Find out how firefly luminescence has become a widely used tool in biotechnology.
Gene Therapy Is Finally Becomi
After the death of several patients during gene therapy trials at the start of the century, there have been several promising trials indicating this approach may be ready for general medical use.
After the death of several patients during gene therapy trials at the start of the century, there have been several promising trials indicating this approach may be ready for general medical use.
Extremophiles
A definition for the term extremophile.
A definition for the term extremophile.
What Technology Really Involves
At the 2013 annual Biotechnology Industrial Organization meeting, four technology transfer executives discussed the challenges and key points for successful technology transfer. They brought up the most essential features of good collaborations and talked about some of the issues that can derail partnerships. (Published: April 23, 2013)
At the 2013 annual Biotechnology Industrial Organization meeting, four technology transfer executives discussed the challenges and key points for successful technology transfer. They brought up the most essential features of good collaborations and talked about some of the issues that can derail partnerships. (Published: April 23, 2013)
Enzymes in the Diary Industry
A description of the most commonly used enzymes in the dairy industry, their sources, applications and notes on genetic modifications that have been made to improve processes.
A description of the most commonly used enzymes in the dairy industry, their sources, applications and notes on genetic modifications that have been made to improve processes.
Pharmacokinetics Defined
Pharmacokinetics is defined as the study of the action of drugs or medicines in living organisms.
Pharmacokinetics is defined as the study of the action of drugs or medicines in living organisms.
CSO
A definition for CSO as it applies to outsourcing and biotech service providers in the pharmaceutical industry.
A definition for CSO as it applies to outsourcing and biotech service providers in the pharmaceutical industry.
Biotech "Firsts"
Biotechnology research would not be where it is today without each one of these significant "firsts".
Biotechnology research would not be where it is today without each one of these significant "firsts".
Dirty Electricity and Health
An interview with Dr. Magda Havas, a scientist from Trent University, Peterborough, Ontario, and a world leader in research on the biological effects of exposure to dirty electricity.
An interview with Dr. Magda Havas, a scientist from Trent University, Peterborough, Ontario, and a world leader in research on the biological effects of exposure to dirty electricity.
Helicos
A case study and company history of Helicos BioSciences Corporation, specialists in single molecule technology, sequencing by synthesis and the innovators of a technique for true single molecule sequencing.
A case study and company history of Helicos BioSciences Corporation, specialists in single molecule technology, sequencing by synthesis and the innovators of a technique for true single molecule sequencing.
DNA Vaccines
The advantages to using DNA vaccines to stimulate immunological responses to infectious and chronic diseases.
The advantages to using DNA vaccines to stimulate immunological responses to infectious and chronic diseases.
What Investors Want
Before approaching a biotech Venture Capitalist for research funding, familiarize yourself with the criteria commonly looked for in startup companies. Compliance with these priorities will increase your chances of attracting investors.
Before approaching a biotech Venture Capitalist for research funding, familiarize yourself with the criteria commonly looked for in startup companies. Compliance with these priorities will increase your chances of attracting investors.
Tools for DNA Sequencing
Molecular techniques that make DNA sequencing possible.
Molecular techniques that make DNA sequencing possible.
Nanotech and Stem Cells
A summary of potential uses for nanotechnology in stem cell applications such as tracking and labeling, delivery and controlling the extracellular environment by creating artifical scaffolds or platforms for directing cell differentiation, migration and adhesion. Toxicity of nanoparticles to stem cells is also discussed.
A summary of potential uses for nanotechnology in stem cell applications such as tracking and labeling, delivery and controlling the extracellular environment by creating artifical scaffolds or platforms for directing cell differentiation, migration and adhesion. Toxicity of nanoparticles to stem cells is also discussed.
Conjugation
Conjugation in bacteria is defined with an explanation of how genetic material is shared between cells.
Conjugation in bacteria is defined with an explanation of how genetic material is shared between cells.
Genencor
Genencor is a biotechnology company specializing in industrial enzymes and environmentally-friendly processes. Their innovative approach to biofuel production has led to development of the Accellerase 1000 enzyme product which results in enhanced bioethanol production from cellulosic feedstocks.
Genencor is a biotechnology company specializing in industrial enzymes and environmentally-friendly processes. Their innovative approach to biofuel production has led to development of the Accellerase 1000 enzyme product which results in enhanced bioethanol production from cellulosic feedstocks.
Therapeutic Cloning
A definition for therapeutic cloning with an explanation of how stem cell research might be used to cure various diseases and repair damaged cells, tissues and organs.
A definition for therapeutic cloning with an explanation of how stem cell research might be used to cure various diseases and repair damaged cells, tissues and organs.
Career Opportunities
Publisher's Site This book is an excellent resource for science job seekers in all areas of the biotechnology
Publisher's Site This book is an excellent resource for science job seekers in all areas of the biotechnology
miRNA
What is miRNA, or microRNA and how is it used as a molecular genetics research tool in the process called RNA interference?
What is miRNA, or microRNA and how is it used as a molecular genetics research tool in the process called RNA interference?
Electrophoresis
Gel electrophoresis is a DNA separation technique, but how does it work?
Gel electrophoresis is a DNA separation technique, but how does it work?
George Washington Carver
George Washington Carver was a pioneer of industrial and agricultural biotechnology, inventing numerous commercial uses for bioproducts obtained from peanuts, soybeans and other crops.
George Washington Carver was a pioneer of industrial and agricultural biotechnology, inventing numerous commercial uses for bioproducts obtained from peanuts, soybeans and other crops.
Delivering New Genes
Gene therapy offers real promise for curing genetic disorders and treating a wider range diseases. How are new functional genes are put into a patients cells? This article describes the main viral DNA vectors used to make the genetic changes required for gene therapy.
Gene therapy offers real promise for curing genetic disorders and treating a wider range diseases. How are new functional genes are put into a patients cells? This article describes the main viral DNA vectors used to make the genetic changes required for gene therapy.
RFPs
A list of items to include in a request for proposals (RFP) when soliciting contract service/ manufacturing organizations for outsourced work including scope of the project, deadlines for submission, fee schedules and required documentation.
A list of items to include in a request for proposals (RFP) when soliciting contract service/ manufacturing organizations for outsourced work including scope of the project, deadlines for submission, fee schedules and required documentation.
pH Indicators
Some common pH indicators with near neutral pka values, and pH ranges making them suitable for use in colorimetric bioassays.
Some common pH indicators with near neutral pka values, and pH ranges making them suitable for use in colorimetric bioassays.